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Overview – What is Soursop?
Soursop is also known as Graviola, Guanabana (in Mexico and Latin America), Prickly Custard Apple, or by its botanical name, Annona muricata. It is a small evergreen tree with shiny green leaves, which grows to a height of about 15′-20′. The green fruit, with tart white flesh it produces, grows in warm tropical regions primarily throughout North and South America. It is often mistaken for “Paw-Paw”, a related plant species.
Is Soursop effective in fighting cancer?
Although no direct evidence or human studies indicating that Soursop fights or cures any form of cancer can be ascertained at this time, a potent group of chemicals from its leaves, bark and seed (called Annonaceous acetogenins) have been successfully isolated. Animal and in-vitro findings using these chemicals were shown to kill or inhibit the growth of various lines of human cancer cells.
What cancer-related studies have been done ?
In in-vitro, various tumor cells, including lung and pancreatic carcinomas, prostate and colon adenocarcinomas, liver cancer, human lymphoma, multi-drug resistant breast adenocarcinomas, ovarian, cervical and skin cancers were killed by the acetogenin chemicals extracted from Soursop.
Mice which inoculated with lung cancer cells were subsequently treated with annonacin (from Graviola) according to a 2002 study. Results showed a 57.9% reduction in their tumors with no toxicity according to a 2002 study. While encouraging, tests of a substance on mice or in test tubes don’t always predict the same results in human. Further testing is underway to assess fully the potential of this supplement.
Research showing the effect of Soursop extract on various types of cancer cells has produced some promising results, which may someday change the future of oncology.
Are there other medicinal uses or health benefits?
People living in areas where Soursop is indigenous have consumed it for a variety of reasons: as a sedative, to stimulate digestion, to reduce fevers, calming nerves, facilitate sleep, reduce tension and blood pressure …even for getting rid of internal and external parasites.
Is Soursop safe?
Some safety data have been published for rats, however there is none yet from clinical trials using human subjects. It may be advisable to consider short-term use with intervals of abstinence and not to exceed recommended dosages. Soursop may interact with some medications and may also be contraindicated for individuals with certain medical conditions. When adding any new supplement to ongoing treatment, you should check with your doctor. As with many herbal supplements, there is no formal rating on this substance. To date there is no reported case from of neurotoxicity from normal use of Soursop by humans as opposed to the known offenders below.
All antidepressants, antipsychotics or neuroleptic drugs on the market approved by the FDA have warnings that they cause toxicity and side effects of Parkinsonism, Extrapyramidal symptoms (tremors, involuntary movements, rigidity) and potentially Tardive Dyskinesia(TD) or irreversible involuntary movements of late onset. 60 millions Americans use these substances every day. Here is an excerpt from the Journal of Clinical Neurology (thejcn.com):
Drug-induced parkinsonism (DIP) is the second-most-common etiology of parkinsonism in the elderly after Parkinson’s disease (PD). Many patients with DIP may be misdiagnosed with PD because the clinical features of these two conditions are indistinguishable. Moreover, neurological deficits in patients with DIP may be severe enough to affect daily activities and may persist for long periods of time after the cessation of drug taking. In addition to typical antipsychotics, DIP may be caused by gastrointestinal prokinetics, calcium channel blockers, atypical antipsychotics, and antiepileptic drugs. The clinical manifestations of DIP are classically described as bilateral and symmetric parkinsonism without tremor at rest. However, about half of DIP patients show asymmetrical parkinsonism and tremor at rest, making it difficult to differentiate DIP from PD. The pathophysiology of DIP is related to drug-induced changes in the basal ganglia motor circuit secondary to dopaminergic receptor blockade. Since these effects are limited to postsynaptic dopaminergic receptors, it is expected that presynaptic dopaminergic neurons in the striatum will be intact. Dopamine transporter (DAT) imaging is useful for diagnosing presynaptic parkinsonism. DAT uptake in the striatum is significantly decreased even in the early stage of PD, and this characteristic may help in differentiating PD from DIP. DIP may have a significant and longstanding effect on patients’ daily lives, and so physicians should be cautious when prescribing dopaminergic receptor blockers and should monitor patients’ neurological signs, especially for parkinsonism and other movement disorders.
Soursop and your immune system
The fruit of Annona muricata is rich in phytochemicals which are believed to have strong antioxidant activity. A number of studies have been done on the antioxidant properties of Soursop. The positive effect of Graviola (Soursop) tea on your immune system was also discussed on a segment on the popular “Doctor Oz” show.
Does Soursop cause Parkinson’s disease?
The people of Guadeloupe in the French West Indies, where Soursop is largely and regularly consumed as food and used as herbal medicine to treat internal parasites, were subjected to an epidemiological studies showing a higher-than-average incidence of a neurological disorder similar to Parkinson’s. There are no medical or scientific studies directly linking this malady to Soursop, however lab tests have shown that an alkaloid from the roots and seeds of the plant to damage certain cells in-vitro and could potentially produce symptoms of this type. Excessive consumption of those parts of the plant should be avoided.
There are so many brands! How do I choose?
Unfortunately, the supplement business is full of unscrupulous companies who cut corners and make outrageous claims to try to make a bigger profit.
Read the label. Avoid products which contain additives or useless fillers.
That famous TV doctor does not endorse any specific products or brands. If a product claims otherwise, that’s should be a big red flag. If they’re stretching the truth about that, what else are they hiding?
For quality and safety reasons, we recommend choosing a supplement which has been manufactured in the USA, preferably in a GMP (Good Manufacturing Practices) certified lab. This assures that the product has been manufactured to rigorous standards and that the bottle actually contains what the label says it does. Are you ready for a 30 day FREE Trial of this supplement?
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